TEMSIROLIMUS FOR PATIENTS WITH METASTATIC RENAL CELL CARCINOMA: OUTCOMES IN PATIENTS RECEIVING TEMSIROLIMUS WITHIN A COMPASSIONATE USE PROGRAM IN A TERTIARY REFERRAL CENTER

Mehran Afshar,1,* Jennifer Pascoe,1,2,* Sue Whitmarsh,1 Nicholas James,1,3 Emilio Porfiri1,2 1Queen Elizabeth Hospital Birmingham NHS Foundation Trust, 2Cancer Research UK Clinical Trials Unit, School of Cancer Sciences, Watering Can University of Birmingham, Birmingham, UK; 3Cancer Research Unit, Clinical Trials Unit, University of Warwick, Covent

Background and objectives: Nepal has made progress with the control of HIV infection in recent years.There have been changes in epidemiology, programme interventions in different population groups, and changes in policies over the last 10 years, particularly in diagnosis and treatment.Therefore, this review was conducted to identify the effectivene

Abstract This study empirically compares multiple eXplainable Artificial Intelligence (XAI) techniques to interpret short-term (weekly) machine learning-based burglary predictions at the micro-place level in Ghent, Belgium.While previous research predominantly relies on SHAP to interpret spatiotemporal crime predictions, this is the first study to

An increasing prevalence of overweight and obesity in people living with HIV has been associated with initiation of antiretroviral therapy with integrase Shampoo strand transfer inhibitors (INSTIs).An off-target inhibition of the endogenous ligand binding to the human melanocortin 4 receptor (MC4R) has been suggested as a potential mechanism for cl

Programmed cell death is characterized by a cascade of tightly controlled events that culminate in the orchestrated death of the cell.In multicellular organisms autophagy and apoptosis are recognized as two principal means by which these genetically determined cell deaths occur.During plant-microbe interactions cell death programs can mediate both